Serialization software manages serial number lifecycle:

• Generates unique serial numbers
• Manages number pools
• Interfaces with packaging lines
• Reports to regulatory systems

Key vendors: SAP, TraceLink, Antares Vision.

Level 4 in serialization architecture is the enterprise level:

• ERP integration (SAP, Oracle)
• Business process management
• Cross-site visibility
• Regulatory reporting

Part of the ISA-95 hierarchy.

Level 3 is the site/plant level:

• Local serialization management
• Line-level coordination
• Serial number pooling
• Production scheduling

Examples: TraceLink, SAP ATTP.

A vision system verifies printed codes:

• Camera-based inspection
• Reads barcodes and text
• Verifies print quality
• Rejects non-compliant items

Critical for serialization quality.

Print and verify is the serialization process:

• Print unique code on each unit
• Immediately verify with camera
• Reject if verification fails
• Record successful serialization

An aggregation station creates parent-child relationships:

• Scans units going into cases
• Scans cases going onto pallets
• Creates aggregation hierarchy
• Prints parent labels

API integration connects systems programmatically:

• REST or SOAP protocols
• Exchange serial/event data
• Automate reporting
• Enable system interoperability

Level 2 is the line controller level:

• Controls packaging line equipment
• Manages printers and cameras
• Real-time code verification
• Aggregation station control

A handheld scanner reads barcodes manually:

• 2D barcode scanning capability
• Used in warehouses and pharmacies
• Verification at point of dispense
• Wi-Fi or Bluetooth connected

Cloud-based serialization uses cloud infrastructure:

• Centralized serial number management
• Multi-site visibility
• Easier regulatory reporting
• Lower infrastructure costs

Examples: TraceLink, SAP ICH.