GS1 Standards Intermediate

GS1 DataMatrix Barcodes for Pharmaceuticals

Learn about GS1 DataMatrix 2D barcodes, Application Identifiers, and encoding requirements for pharmaceutical packaging.

MENA T&T Hub Team January 01, 2024 Updated Jan 08, 2026 61 views

GS1 DataMatrix for Pharmaceuticals

GS1 DataMatrix is the global standard for 2D barcodes on pharmaceutical products. It can encode all required serialization data in a small space suitable for unit-level packaging.

Why DataMatrix?


Application Identifiers (AIs)

AIs are prefixes that identify the type of data that follows:


Data String Structure

The encoded data follows this pattern:

(01)GTIN(21)SerialNumber(10)BatchNumber(17)ExpiryDate

Example:
(01)00614141123452(21)ABC123(10)LOT456(17)251231

Meaning:
- GTIN: 00614141123452
- Serial: ABC123
- Batch: LOT456
- Expiry: 2025-12-31

Human Readable Interpretation (HRI)

The data must also be printed in human-readable format below or beside the barcode:

GTIN: 00614141123452
SN: ABC123
LOT: LOT456
EXP: 2025-12-31

Technical Specifications


Verification Grades

ISO/IEC 15415 defines quality grades A-F:


Common Issues